Should Parents Opt for Private Cord Blood Banking?

Expecting a baby is one of the beautiful yet important phases of life. Several decisions are to be made and what to do with your newborns cord blood is just one of them. Cord blood is a precious commodity that is collected from a newborn right after birth. Being a rich source of stem cells, cord blood is currently used to treat more than 80 diseases including several forms of cancers, immune disorders, blood disorders and genetically inherited diseases to mention a few. Parents may discard it, donate it to public banks or store it in a private cord blood banking facility. Storing cord blood and tissue at private banks may cost you whereas donations are free of cost. Cord blood donated to the public bank is used either for medical research or stem cell transplants.

Private cord blood banking have been gaining immense popularity in the recent times, as you can find its marketing pitches everywhere – at doctor’s waiting rooms, pregnancy related mobile apps, parenting magazines and more. The month of July is even considered as National Cord Blood Awareness Month. But according to the doctors, parents need to be very cautious when signing up for the private cord blood storage. Expectant parents need to think long and hard before taking an informed decision. Banking your newborns cord blood at a private bank is an expensive affair, as the processing fees can run from roughly $500 to $2,500 with the annual storage fees of $100 to $300 each year thereafter.

Most of the parents who opt for private cord blood banking consider it as a precious resource and biological life insurance for their kid. Even though, the chances of your child benefiting from his or her own cord blood are less than 0.04 percent. This is because the cord blood contains the same cells and genetic defects that are responsible for the diseases in the first place. So, the best case is to choose private banking only if your family has a medical history of diseases currently treatable with cord blood. Talk with your doctor in order to discuss all the possibilities and take a wise decision.

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What is Cord Blood Banking?

Promising results from cord blood research have been prompting more and more parents to bank their newborn’s umbilical cord blood and tissue. As a rich source of stem cells, cord blood is currently used in several lifesaving transplants and is expected to cure more debilitating conditions in the future. Patients with leukemia, lymphoma, immune deficiencies and other inherited metabolic disorders can benefit from cord blood stem cell transplants.

What makes cord blood so unique and valuable? Until recently, the blood present in the placenta and umbilical cord was disposed as medical waste right after the child birth. But with the discovery of the abundance of stem cell in the cord blood, things have changed. Stem cells present in the cord blood are capable of dividing and renewing themselves. Since they are unspecialized templates, these cells can be developed into specialized cells and tissues. It is their renewal property that proves beneficial in treating several life threatening conditions. During stem cell transplants, the damaged cells are destroyed and replaced with cord blood stem cells, which then replicates and produce new blood cells.

What is cord blood banking? Collecting and storing the newborn’s cord blood for long term is known as cord blood banking. Private and public cord blood banking options are available for the expectant parents. According to researchers and scientists, cord blood holds an immense potential as a treatment for a diverse range of health conditions, such as cerebral palsy (CP), stroke, spinal cord injuries, diabetes, and cardiovascular disease. Several clinical trials and research sessions are underway exploring the therapeutic value and applications of cord blood and cord tissue stem cells.

If you are an expectant parent, then you may either decide to store your baby’s cord blood at a private bank or donate it to a public bank. A number of patients suffering from conditions like those listed above may benefit from the public stem cell donations. So, rather than waste this valuable resource, make a point to store or donate your infant’s cord blood and cord tissue.

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Banking Cord Blood Stem Cells

Expectant parents have a number of major decisions to make as they prepare to welcome the new member to family. One of the big financial decisions is about banking the cord blood. If you are wondering what is cord blood, then let us explain. The umbilical cord that connects the mother to the growing fetus is cut after the birth. A small amount of blood remains in the blood vessels of the placenta and cord even after the delivery, which is termed as cord blood. In addition to the normal elements of blood (red blood cells, white blood cells, platelets and plasma), cord blood contains multipotent stem cells. These unspecialized cells with self-renewing capabilities can give rise to other cell types. However, the specialization potential of multipotent stem cells is limited to one or more cell lines. Presence of mutipotent stem cells in cord blood and cord tissues makes it life saving resource. And that is why medial communities are encouraging the expectant parents to bank or donate the cord blood rather than throwing it away. Cost of cord blood banking is worthy, especially if your family has a history of genetic disease.

Newborn’s cord blood is used for treating several life threatening disorders including several forms of leukemia, lymphoma and anemia. Hematopoietic stem cells or blood forming stem cells found in the umbilical cord blood is used as an alternative to bone marrow for transplantations. Bone marrow donation demands surgery whereas cord blood stem cell collection poses no medical risk or incisive procedures. Severe graft vs host disease (GvHD) is common with mismatched grafts of bone marrow transplants, but the chances of GvHD is less frequent and easier to treat among the cord blood transplant patients. Umbilical cord blood stem cells are used for transplants and regenerative medicine research. Scientists and experts believe that cord blood and cord tissue stem cells have the potential to revolutionize the future of medicine.

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How Cord Blood Stem Cell Banking Works?

Umbilical cord blood stem cell banking is rapidly becoming popular among the expectant parents. Being a hot topic of discussion among the scientific and medical community, cord blood banking have been gaining immense popularity across the globe. Though the private cord blood banking prices are higher, chances your family will use the blood is low. Doctors often encourage the expectant parents to donate their newborn’s umbilical cord tissue and cord blood. Donations made to a public cord blood bank are used for several life-saving stem cell transplants and regenerative medicine therapy research. But if your family has a medical history of genetically inherited diseases such as leukaemia, lymphomas, sickle-cell anaemia, immune deficiency disorders, aplastic anaemia and thalassaemia, then you may consider banking your baby’s cord blood privately. Seeking the guidance of your family doctor is strongly recommended before taking an informed decision.

What are the major steps involved in the cord blood stem cell banking process? If you have decided to bank your infant’s cord blood and umbilical cord tissue, then it is essential to complete the enrollment process in the early stages of pregnancy. Choose a reputed private cord blood bank and sign up for their services. A collection kit will be provided to you upon enrollment. Make it a point to inform your doctor about your cord blood banking decision. Also, remember to carry the kit with you when leaving the hospital for delivery. Right after the child birth, the cord blood and tissue is collected to the sterile bag.  Collection process is simple, safe and quick, as it neither poses any risk to mother or baby. Collected samples are couriered to the cord blood bank through specialized logistics for ensuring safe delivery. As soon as the samples reach the bank, they are individually tested and processed. Stem cells harvested from the cord blood are mixed with cryopreservatives for long term storage. Later, these stem cells are frozen down slowly and then placed inside large stainless steel tanks supplied with liquid nitrogen so that the stem cells remain preserved for decades.

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Future of Umbilical Cord Stem Cell Banking

The field of stem cell research and regenerative medicine has been advancing at a rapid rate over the past decade. For those who are wondering about the hype surrounding stem cell biology – stem cells or master cells have the remarkable property to self-replicate throughout the life of the organism. Moreover, they can give rise to specialized cells which further take the place of damaged or dead cells. Unlike other mature cells that are permanently committed to their function, stem cells have a unique property to renew themselves and develop into specialized cells of the body. Major sources of stem cells include bone marrow, umbilical cord, embryo and adipose tissue.

Scientists around the world have been striving hard to take advantage of stem cell’s unique characteristics in order to apply in clinical applications and therapeutics. Stem cell banking is the practice of harvesting stem cells for long storage for transplants or research purpose. However, embryonic stem cell banking has steeped in ethical controversy centered on embryo destruction. That is where the role of umbilical cord stem cell banking takes the limelight. Umbilical cord blood, once discarded as per medical status, is now treasured by the medical communities. The cord blood that provides nourishment to the growing fetus is a great source of stem cells. Nowadays, the umbilical cord blood and tissue is collected right after the child birth.

Expectant parents have the choice to either store or donate their newborn’s cord blood and umbilical cord tissue. Hematopoietic stem cells (HSCs) present in the cord blood is used as an effective alternative to bone marrow transplantation whereas Mesenchymal StemCells (MSCs) in umbilical cord tissue can potentially be used in a variety of regenerative medicine and tissue engineering applications. Paying annual private cord blood banking prices may prove worthy for the families with a history of immune deficiency diseases, leukemia, lymphomas and similar conditions.

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Importance of Umbilical Cord Tissue

Why save baby cord blood? What are its benefits? Is it worth the money? Blood present in the baby’s umbilical cord contains stem cells. Multipotent adult stem cells present in the umbilical cord blood make it a precious resource in the medical and research field. And that is why baby’s cord blood, which was once discarded as medical waste, is now collected and saved for long term storage. The first human transplant using cord stem cells was performed in 1988. It was for treating Fanconi anemia – an inherited disease that mainly affects the bone marrow. Cord blood that was used to treat only one disease at that time can now treat nearly 80 diseases.

Hematopoietic stem cells (HSCs) present in the baby cord blood can be used to restore the damaged blood cells in our body. Developed from mesodermal hemangioblast cells, HSCs are self-renewing progenitor cells that has the potential to generate multitude of cell types found in the blood stream including red blood cells, white blood cells and megakaryocytes. Hematologic and nonhematologic cancers, autoimmune disorders, various forms of anemia and immunodeficiency disorders can be treated with the cord blood Hematopoietic stem cell transplants (HSCTs). Why cord blood stem cell transplants are gaining wide acceptance in the medical community? Cord blood stem cell transplants require a less-stringent HLA match and carry a lower risk of graft-vs-host disease. Moreover, the transplant outcomes are more effective and better with cord blood applications when compared to other transplant methods.

Stem cells are not only present in the cord blood, but also in the surrounding tissue.  Umbilical cord tissue is a rich source of Mesenchymal stem cells (MSCs). This type of multipotent connective tissue cells can develop into a variety of cell types such as bone cells, cartilage cells, muscle cells and fat cells. Many scientists are striving harder to discover the cord tissue benefits and applications. Currently research and clinical trials are going on to better understand the potential of cord tissue. According to the scientists, cord tissue MSCs can be used to treat Liver fibrosis, Parkinson’s disease, Rheumatoid arthritis and lung cancer to name a few.

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Banking Umbilical Cord Blood and Cord Tissue

From diagnostic tools to treatment modalities, innovative advancements in the medical technology have been offering promising solutions to increase the quality of patient’s life and cure the root cause of debilitating conditions effectively. Introduction of umbilical cord blood stem cell transplants is a case in point. Umbilical cord which connects the mother to a developing fetus has mainly two layers – an outer layer of smooth muscle and inner layer made from gelatinous Wharton’s jelly. The cord has one vein and two arteries. Vein supplies oxygen and nutrient-rich blood to the fetus whereas arteries take away the nutrient depleted and deoxygenated blood from the fetus.

Blood from the umbilical cord is an abundant source of multipotent Haematopoietic stem cells (HSCs) and can be used to treat a number of life threatening conditions. Moreover, it is also used for the regenerative medicine research and clinical trials. Not just the cord blood (CB), but the umbilical cord tissue also contains Mesenchymal stem cells (MSCs). Currently, HSCs are used to treat more than 80 diseases including leukemias, lymphomas, anemias and Severe Combined Immunodeficiency (SCID). On the other hand, umbilical cord tissue is not yet used in the medical applications or clinical practice. However, researchers firmly believe that the cord tissue’s MSCs has the potential to treat spinal cord injuries, heart disease, arthritis, stroke, alzheimer’s and type 1 diabetes.  Several clinical trials and studies are underway to explore the promising applications and therapeutic benefits of cord tissue MSCs. And that is why medical communities consider umbilical cord blood and tissue as a precious resource.

If you are an expectant parent, then you may either choose to bank your newborn’s cord blood or donate it. You should discuss the matter with your family doctor and family member before taking a final decision. Families with a medical history of inherited diseases may opt for private cord blood banking. No matter whether you decide to bank or donate your newborn’s CB, choosing a reputed cord blood bank is significant.

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Banking Your Baby’s Umbilical Cord Blood

Placenta and umbilical cord are the two crucial support systems of a healthy pregnancy. Placenta not only provides nourishment to the growing fetus but also takes away the waste from the fetus to mother’s system for excretion.  The cord structure that connects placenta to the fetus is called umbilical cord. Known as the lifeline between mother and baby, umbilical cord carries oxygenated blood from placenta to baby through its vein and takes away deoxygenated blood from baby to placenta through its arteries.

Blood present in the umbilical cord, which was once considered as a medical waste, is now known to be a valuable resource. Abundant presence of stem cells in the newborn’s umbilical cord blood (CB) makes it a lifesaving resource and that is why the medical community is encouraging the storage of cord blood stem cells. Used to treat more than 70 types of diseases including leukemia, lymphoma, sickle-cell disease, metabolic disorders and some inherited disorders, newborn’s umbilical cord blood holds a promising future in regenerative medicine therapies.

Several clinical trials are still underway, where scientists and researchers are striving harder to unlock and tap into the potential of cord blood and cord tissue stem cells. Unlike the bone marrow stem cell harvesting, cord blood collection and stem cell banking is a painless procedure that doesn’t require any invasive methods. Easy and quick CB collection carried out immediately after the delivery neither hurts the mother nor the baby. Expectant parents may check out informative cord blood banking videos and webinar sessions to explore the benefits and downsides of CB.

The first successful cord blood stem cell transplant took place in 1988 at Hospital Saint-Louis in Paris. Performed for treating Fanconi’s anemia, this transplantation was a new milestone in the history of stem cell research. The patient was a five year old boy named Matthew Farrow and he received the donor stem cells from his newborn baby sister. Since then, cord blood stem cell banking and donations have reported a surging growth and popularity.

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Baby’s Cord Blood – Store or Donate?

An expectant parent needs to take a number of important decisions in order to ensure the future health of their child. What to do with the newborn’s cord blood is a case in point. Blood present in the umbilical cord is an abundant source of stem cells which makes it a valuable lifesaving resource. It can be used to treat an array of debilitating conditions such as leukaemia, lymphoma and anaemia to mention a few. And that is why cord blood banking have been gaining wide acceptance like never before. With the remarkable advancements in the stem cell research, the field of cord blood stem cell technology is all geared up to transform the regenerative medicine in many ways. Expectant parents can discard it, donate it to a public cord blood bank or store it in private cord blood banks.

You need to take several factors into consideration before taking a decision. Having a look at your family medical history is one of them. Check whether there are any heritable diseases running in your family that can be treated with cord blood. Have a brief discussion with your family members and seek the guidance of your family doctor. Private cord blood banks store your baby’s cord blood for an annual fee so that the family can use it at the time of need. If you have decided to bank your baby’s cord blood, then it is advised to do a detailed research to find an accredited and reputed family cord blood bank.

Public cord blood banks allow families to donate the blood at free of cost. Cord blood donated to such public facilities is used for transplants or medical research. No matter whether you are planning to store or donate cord blood, it is essential to check out the eligibility criteria of cord blood banking.

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Baby Cord Blood for Stem Cell Transplants

Significant strides and breakthroughs in the medical research and healthcare have helped the physicians to diagnose and treat patients better. Let us consider the field of stem cell research. Scientists have been striving hard to tap into the potential of master cells in curing wide and extensive array of diseases. Several discoveries were made over the past decade and the use of baby cord blood for stem cell transplants was just one of them. Umbilical cord blood that connects an embryo to the placenta serves an integral role of providing nutrients to the growing fetus. Discovery of stem cell presence in the cord blood and cord tissue was a major milestone in the history of stem cell research. Blood forming hematopoietic stem cells present in the cord blood can develop into red cells, white cells or platelets, which makes it capable of curing different types of debilitating conditions including genetic disorders, immune deficiencies and blood disorders. On the other hand, umbilical cord tissue contains Mesenchymal stem cells that can develop into different skeletal tissues such as cartilage, bone and fat.

Cord blood, being a rich source of blood forming stem cells can be used for the transplants among leukemia patients so as to restore the body’s ability to make blood and immune cells. That is the reason why medical community and scientists have been encouraging the banking and donation of baby cord blood. Private and public cord blood stem cell banking services are available to the expectant parents. Blood stored in the private bank will be solely for the family whereas cord blood donated to the public bank will be used for life saving transplants and research purpose. Great shelf life, lower risk of viral contamination, higher flexibility and lower incidence rates of graft versus host disease are some of the major benefits that makes cord blood stem cells a better alternative over bone marrow transplants.

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